The Main Therapy for Fast and Persistently Improving All Degrees of Hepatic Encephalopathy
Each 1000 mL Aminoleban Infusion, contains :
Amino Acids : 7.99 %
Branched-Chain Amino Acid (BCAA) : 35.5 %
Arginine : 7.3 g
Fischer’s Ratio : 37.05
E/N Ratio : 1.09
Total Nitrogen : 12.2 g/L
Na+ Approx : 14 mEq/L
Cl- Approx : 94 mEq/L
Osmolarity : 768 mOsm/L
Treatment of hepatic encephalopathy in patients with chronic liver disease.
Dosage and Administration :
Adult : 500 – 1000 mL by intravenous drip infusion. The usual peripheral infusion rate is 500 mL over 180-300 minutes in adult ( approx. 25-40 drops per minute ).
For Total Parenteral Nutrition : 500 – 1000 mL of the injection should be suitably combined with dextrose or other solution and administered over 24 hours via the central vein. The dosage may be adjusted depending on the patient’s age symptoms and body weight.
Contra Indications :
Patients with severe renal disorder (the amount of water tends to be excessive and the patients clinical condition may be worsened. Urea and other amino acid metabolites may be retained, which may worsen the patients clinical condition )
Patients with abnormal amino acid metabolism (since the infused amino acids are not adequately metabolized, the patient’s clinical condition may be worsened)
Careful administration in patients with severe acidosis and congestive heart failure.
Used in children : the safety of Aminoleban Infusion in children has not been established.
Adverse Reactions :
Hypersensitive skin rashes or other hypersensitive reactions have been rarely reported and administration should be discontinued if such signs develop.
Digestive : Nausea and Vomiting may infrequently occur.
Large dose and rapid administration : Acidosis may occur after a rapid and large dose of Aminoleban Infusion.
Others : Chills, Fever, headache and vascular pains may infrequently occur.